Leukemia Stem Cells in Hematologic Malignancies

Leukemia Stem Cells in Hematologic Malignancies (eBook)

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This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies. It addresses the role of leukemia stem... (weiter)

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Details
Edition 1st ed. 2019
EAN 9789811373428
erschienen bei Springer-Verlag GmbH
Erstverkaufsdatum 23.07.2019
Serien Advances in Experimental Medicine and Biology
Stichwörter blood cancer
targeted therapy
drug resistance
disease relapse
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This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies. It addresses the role of leukemia stem cells in different leukemia diseases and molecular signatures, as well as the metabolic and epigenetic regulation of leukemia stem cell function. With regard to solid tumors, a significant number of blood cancers are believed to be derived from leukemia stem cells (LSCs), which are responsible for disease progression, relapse and drug resistance. Consequently, new therapeutic strategies need to be developed by focusing on the complete eradication of LSCs. Given its scope, the book offers a valuable asset for graduate students and scientists in the fields of cell biology and cancer research etc.

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